Midwest Train Routes

Amtrak in the Midwest means not only making connections between eastern and western long-distance trains in Chicago at the center of our national system, but also means frequent daily departures between Chicago and key cities in the five-state area, including Illinois, Indiana, Michigan, Missouri and Wisconsin. Explore each route below to start your midwest adventures.

Featured Midwest Route

Empire Builder

Chicago - St. Paul/Minneapolis - Spokane - Portland/Seattle

Marvel at the majesty of the northern United States as you travel over mountain passes, through alpine valleys and past 7,000-year-old glaciers. Glide by buttes and bluffs, along mountain streams and across the Mighty Mississippi. With stops in big cities and quaint mountain towns, the Empire Builder invites you to experience culture, nature and rapture in one grand adventure.

"Earth and sky, woods and fields, lakes and rivers, the mountain and the sea, are excellent schoolmasters, and teach some of us more than we can ever learn from books." — Sir John Lubbock