Located in the bustling heart of San Diego, Santa Fe Depot is the California gateway to a national network of trains connecting the continental United States and Canada.
Take a look at the full list of Amtrak's California train routes for the essential details on amenities, accommodations, menus, local guides, route highlights and much more.
Ready to go right now? Buy train tickets to San Diego here (above with the Fare Finder), from the Amtrak app, at an Amtrak kiosk or from a ticketing agent at any Amtrak station.
Ways to Save with Our Discounts and Deals
Discover all of the ways to save on train fares with our latest deals, discounts and flexible ticket options. Here's how to always find the lowest prices Amtrak has to offer:
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Learn More About Our Seniors DiscountPopular Amtrak Rides to San Diego
Your journey begins by finding an Amtrak station near you. Click any of the below station names to get directions. Don't see your starting city? Use "Plan" and "Find Station/Route" in the main menu above to search.
Things To Do in San Diego
Arrive Downtown, Not Out of Town
Stepping off the train at San Diego’s Santa Fe Depot places you right in the heart of downtown, surrounded by attractions that are easy to explore on foot. Just a short walk away, the Embarcadero offers waterfront views, public art, and access to San Diego Bay, making it a must-see stop for travelers arriving by Amtrak. Nearby culture landmarks like the USS Midway Museum and the Museum of Contemporary Art San Diego reflects the city’s vibrant mix of history, art and coastal culture.
Right outside the station, the neighborhood is filled with coffee shops, casual restaurants and boutique stores. From here, it's an easy walk to the waterfront, where you can enjoy open-air patios, seafood spots and views of ships and ferries moving through the harbor. Whether you're stopping by for a quick visit or starting a longer stay, the area around Santa Fe Depot offers a relaxed blend of coastal atmosphere and city life.
Arrive Downtown, Not Out of Town
Stepping off the train at San Diego’s Santa Fe Depot places you right in the heart of downtown, surrounded by attractions that are easy to explore on foot. Just a short walk away, the Embarcadero offers waterfront views, public art, and access to San Diego Bay, making it a must-see stop for travelers arriving by Amtrak. Nearby culture landmarks like the USS Midway Museum and the Museum of Contemporary Art San Diego reflects the city’s vibrant mix of history, art and coastal culture.
Right outside the station, the neighborhood is filled with coffee shops, casual restaurants and boutique stores. From here, it's an easy walk to the waterfront, where you can enjoy open-air patios, seafood spots and views of ships and ferries moving through the harbor. Whether you're stopping by for a quick visit or starting a longer stay, the area around Santa Fe Depot offers a relaxed blend of coastal atmosphere and city life.
Amtrak Always: Why You’ll Love Taking the Train to San Diego
When it comes to having a great trip, the travel experience can make a world of difference. That’s why Amtrak is committed to being more than just your mode of transportation from point A to point B. Our unique offerings are dedicated to giving you a better way to travel. Ditch the middle seats and hidden fees of plane travel and leave your car trip and gas price worries at home.
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*The subtitle sample price comes from Los Angeles, CA and was found by others in the previous 48 hours for one-way trips, which may not currently be available.
